🌿 Low Dose Naltrexone (LDN) for Long COVID Recovery
By Dr. Devin Wilson, ND | Valley Integrative Health
Understanding Long COVID
For many people, recovery from COVID-19 isn’t straightforward. Weeks or even months after infection, symptoms like fatigue, brain fog, pain, shortness of breath, anxiety, poor sleep, and exercise intolerance can persist. This lingering condition—known as Long COVID or Post-Acute Sequelae of SARS-CoV-2 infection (PASC)—often results from ongoing inflammation, immune system imbalance, and mitochondrial dysfunction.
In other words, the body’s immune system stays “switched on,” leading to exhaustion, tissue inflammation, and nervous system dysregulation.
What Is Low Dose Naltrexone (LDN)?
Low Dose Naltrexone (LDN) is a safe, affordable, and non-addictive therapy that helps modulate the immune system and reduce inflammation.
At standard doses, naltrexone blocks opioid receptors, but in low doses (1.5–4.5 mg), it acts differently—stimulating the body’s own production of endorphins, which calm inflammation, improve immune balance, and promote healing.
How LDN Helps With Long COVID
LDN supports recovery from Long COVID by addressing the root drivers of lingering symptoms:
🌿 Regulates immune activity – helps reset overactive immune cells, reducing chronic inflammation.
🌿 Decreases neuroinflammation – calms overactive microglia in the brain to improve mental clarity and focus.
🌿 Boosts endorphins – naturally improves energy, sleep, and mood.
🌿 Restores balance – supports the body’s natural healing rhythm without suppressing the immune system.
Many patients report improved energy, less pain, and better mental clarity within several weeks of use.
Complementary IV Therapies for Long COVID
At Valley Integrative Health, LDN is often paired with targeted IV nutrient therapies to accelerate healing and reduce inflammation:
💧 IV Ozone Therapy – supports oxygen utilization, reduces viral load, and calms systemic inflammation by improving mitochondrial function.
💧 IV Glutathione – the body’s master antioxidant, helping detoxify cells, clear inflammation, and restore immune balance.
💧 IV NAD+ (Nicotinamide Adenine Dinucleotide) – boosts cellular energy, supports brain function, and repairs mitochondria damaged by infection or oxidative stress.
These IV therapies are customized based on each patient’s lab findings, energy levels, and detoxification needs, working synergistically with LDN for a stronger, faster recovery.
Our Integrative Approach
Dr. Devin Wilson combines LDN and IV therapies within a holistic, evidence-based framework that includes:
Functional lab testing to identify lingering inflammation and nutrient depletion
Gut and liver support for improved detoxification
Nutritional and mitochondrial optimization
Gentle immune and nervous system regulation
This whole-person approach helps patients restore energy, resilience, and quality of life.
Safety and Tolerability
LDN is generally very well tolerated. Mild, temporary effects like vivid dreams or short-term sleep changes can occur during the first week or two, but these typically resolve quickly. Because LDN supports rather than suppresses immune function, it’s safe for long-term use and integrates well with most other treatments.
Start Your Recovery Journey
If you’re struggling with Long COVID, there is hope.
At Valley Integrative Health, we specialize in helping patients rebuild energy, reduce inflammation, and restore vitality through personalized care plans that may include LDN, IV ozone therapy, glutathione, and NAD+.
Contact Valley Integrative Health Today.
Devin Wilson, ND is a licensed Naturopathic Doctor and Owner of Valley Integrative Health, LLC in Ashland, Oregon. With over a decade of clinical experience including 2 years of training with a John’s Hopkin’s/Yale Medical Doctor, Dr. Wilson combines naturopathic and modern medicine along with cutting-edge therapies. His enduring goal is to help people re-establish, maintain and optimize their health using a patient-centered and holistic approach.
Schedule a Free 15-Minute Discovery Call to learn if this approach is right for you.
📞 541-646-9186
🌐 www.VIHclinic.com
📍 1661 Hwy 99 N, Suite 203-F, Ashland, Oregon